Oxidative stress telomere shortening

we investigated whether oxidative stress, which contributes to aging, accelerates the telomere shortening in human cultured cells.

does oxidative stress shorten telomeres in vivo? a review

06.12. oxidative stress is presumed to be a major cause of telomere shortening, but most evidence to date comes from in vitro cultured cells.

does oxidative stress shorten telomeres? biology letters

abstract ıntroduction telomeres structure and. what is the current evidence.

role of oxidative stress in telomere shortening in cultured fibroblasts

03.05. oxidative stress shortens telomeres in cell culture, but whether oxidative stress explains variation in telomere shortening in vivo at .

stress and telomere shortening: ınsights from cellular mechanisms

ıncreased telomere shortening upon oxidative stress in a–t cells was associated with a significant increase in the number of extrachromosomal fragments of .

oxidative stress ınduces persistent telomeric dna damage

telomere shortening also happens through oxidative damage and other end processing events, in both dividing and nondividing cells.

accelerated telomere shortening in response to life stress pnas

29.10. oxidative stress that produces ros has been shown to accelerate telomere shortening in replicating fibroblasts in vitro [47]. other studies have .

telomere length and oxidative stress and ıts relation with

most notably, in vitro, oxidative stress can shorten telomeres and antioxidants can decelerate shortening 9, 10. perceived stress has been linked to one .

association between oxidative dna damage and telomere

a link between telomere length and some agerelated diseases has been identified, including metabolic syndrome. so far, there is no mechanism to explain the .

telomere shortening and oxidative stress in aged macrophages

shortening is highly dependent on cellular oxidative damage. this study analyzed the relationship between telomere shortening and oxidative.

vitamin e supplementation—but not ınduced oxidative stress

15.08. thus, these results point to telomere shortening as the molecular determinant of some aspects of macrophage aging by modulating oxidative stress .

telomere shortening and oxidative stress in patients with copd

21.05. telomere length is a marker of cellular senescence that relates to different nents of individual fitness. oxidative stress is often .

different effects of accelerated development and enhanced growth

conclusions: telomere length was associated with oxidative stress in copd patients. and its rate of shortening seems to be related with a decrease in lung .

study finds direct oxidative stress damage shortens telomeres

08.08. oxidative stress and relative telomere length. we found several alterations in the activity of antioxidant enzymes and in oxidative damage in .

telomerase can't handle the stress

09.07. the same sources thought to inflict oxidative stress on cells — pollution, diesel exhaust, smoking and obesity — also are associated with .

telomerase does not counteract telomere shortening but protects

in telomerase upon exposure of cancer cells to oxidative stress. ıt has long been known that telomeres the impact of ros on telomere length maintenance.

a putative model of carcinogenesis in fanconi anemia cells.

01.04. we show here that tert, the catalytic subunit of human telomerase, protects human fibroblasts against oxidative stress. while tert maintains .

correlation between telomere length and biomarkers of oxidative

16.11. the role of oxidative stress on telomere shortening, telomere dysfunction and damage to telomere g strand overhang a putative model of .

ergothioneine mitigates telomere shortening under oxidative

03.02.2022 now the question arises—ıs there any correlation between oxidative stress and the telomere shortening during aging? there have been several .

a continuous correlation between oxidative stress and telomere

07.12.2020 shortened telomeres are associated with aging and agerelated diseases. oxidative stress is thought to be a major contributor to telomere .

ınduction of site

telomere shortening in cells with low intrinsic telomerase activity like fibroblasts is governed by various mechanisms including the socalled .

stress induced telomere shortening: longer life with less mutations?

abstract. chronic oxidative stress is the major endogenous metabolic stress and contributes directly to telomere shortening and senescence. understanding the .

telomere length and oxidative stress in the progression of

01.03. telomeres shorten at every cell division and cell stops dividing once the genotoxic stress, e.g. oxidative stress, replication of dna .

association of telomere length with type 2 diabetes, oxidative stress

27.06. since telomere length is believed to reflect environmental effects rather than cell division, specifically in mice [30], the increase in .

oxidative stress, telomere length, and frailty in an old age

04.11. high oxidative stress potentially leads to accelerated telomere shortening and consequent premature cell senescence, implicated in type 2 .

telomere shortening and stress

telomere length could eventually be used as a marker to differentiate between healthy and unhealthy aging as expressed by frailty phenotype; oxidative stress .

how can ı protect my telomeres and slow aging?

02.02.2021 apart from the aforementioned oxidative stress, research has linked other physiological effects of psychological stress to telomere length.

lower antioxidant capacity and elevated p53 and p21be a link

12.01. which environmental factors cause telomere shortening? chronic exposure to dna damaging agents e.g. uv, oxidative stress, and inflammation .

mechanism of telomere shortening by oxidative stress semantic

01.02. oxidative stress has been shown to accelerate telomere shortening and ın addition, telomere length, senescent proteins, and antioxidant .